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The capsular polysaccharide of Neisseria meningitidis serogroup C, composed primarily of α(2→9)-linked N-acetylneuraminic acid, is a critical virulence factor enabling immune evasion. It serves as the primary antigenic target for both polysaccharide and conjugate vaccines aimed at preventing invasive meningococcal disease caused by this serogroup.
Antibody-mediated complement activation and opsonization, induction of long-lasting immunity
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