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Target intelligence / Profile preview
Neisseria meningitidis serogroup A capsular polysaccharide conjugate antigen (Nm serogroup A CPS conjugate antigen)
- Target
- Nm serogroup A CPS conjugate antigen
- Molecular classification
- Polysaccharide, Conjugate Vaccine Antigen
01
Overview
The Neisseria meningitidis serogroup A capsular polysaccharide conjugate antigen is a key component in vaccines designed to prevent invasive disease caused by Neisseria meningitidis serogroup A. This antigen consists of the purified capsular polysaccharide from N. meningitidis serogroup A, which is chemically linked (conjugated) to a carrier protein such as diphtheria toxoid or tetanus toxoid. The conjugation enhances immunogenicity, especially in young children, by inducing a T-cell dependent immune response.
- Other names
- Serogroup A capsular polysaccharideN. meningitidis serogroup A CPSPsA-TTGroup A Meningococcal Conjugate Vaccine AntigenMenA CPS Conjugate
02
Mechanism of action
Stimulates production of antibodies specific for the group A capsule, facilitating clearance of bacteria via phagocytosis and complement activation.
03
Biological functions
AntigenImmune response inductionBacterial opsonization
04
Disease associations
InfectionMeningococcal disease
05
Interacting drugs
MenAfriVac
1 more in the full profile.
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