Target intelligence / Profile preview

Neisseria meningitidis serogroup W‑135 capsular polysaccharide antigen (None)

Target: None
Molecular classification: Polysaccharide, Capsular Polysaccharide, Antigen

Overview

The Neisseria meningitidis serogroup W-135 capsular polysaccharide antigen is a group-specific carbohydrate structure that forms the outer capsule of N. meningitidis bacteria belonging to serogroup W-135. This capsule is a major virulence factor, enabling the bacterium to evade host immune responses and cause invasive diseases such as meningitis and septicemia. It serves as a key component in vaccines to induce protective immunity.

Other names: Meningococcal group W‑135 polysaccharideNeisseria meningitidis group W‑135 capsular polysaccharide antigenMeningococcal polysaccharide antigen group W‑135NM-W-135 CPS antigen

Mechanism of action

Induces antibody production targeting the capsular polysaccharide, leading to opsonization and complement-mediated killing of Neisseria meningitidis serogroup W-135.

Biological functions

Immune evasionVirulence factorAntigen presentation (via vaccines)

Disease associations

MeningitisSepticemiaInfection

Interacting drugs

Menquadfi

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