Nerve tissue development

Nerve tissue development" refers to the highly regulated sequence of events by which the nervous system forms during embryogenesis. This includes induction from ectodermal cells via signals from mesoderm-derived structures like the notochord; formation and closure of the neural tube; migration and differentiation into neurons and glial cells; axon guidance via chemotactic cues such as ephrins/Eph receptors; synaptogenesis; myelination by oligodendrocytes in CNS or Schwann cells in PNS; and refinement/remodeling based on electrical activity. Key signaling molecules involved include bone morphogenetic proteins (BMPs), fibroblast growth factors (FGFs), Sonic hedgehog protein (Shh), Notch pathway components, semaphorins, ephrins/Eph receptors among others. Disruptions at any stage can result in congenital neurological disorders or contribute to later neuropsychiatric disease risk[1][2][3][5][7].

Other names

Neural developmentNervous system developmentNeurogenesisNeural differentiation

Not applicable for the same reason—mechanisms would relate to modulation of underlying signaling pathways like BMP/Smad, FGF/MAPK/ERK, Notch, Sonic hedgehog etc.