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Neural Stem Cell (NSC)
- Target
- NSC
- Molecular classification
- Stem Cell, Multipotent Cell
01
Overview
Neural stem cells are self-renewing, multipotent stem cells found in the nervous system with the capacity to proliferate and differentiate into neurons, astrocytes, and oligodendrocytes. They play a crucial role in development, neurogenesis, and regeneration, making them a target for treating neurological disorders.
- Other names
- Neural precursor cellNeural progenitor cell
02
Mechanism of action
Modulation of NSC proliferation, differentiation, and survival
03
Biological functions
Self-renewalDifferentiationNeurogenesisBrain plasticityTissue regeneration
04
Disease associations
Neurodegenerative diseasesTraumatic brain injuryAlzheimer's diseaseParkinson's diseaseSpinal cord injuryAgingNeurological disorders
05
Safety considerations
Risk of tumor formation (teratoma) following transplantationOff-target effectsUncontrolled differentiationImmune rejection
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