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Neuroepithelial cell transforming 1 pseudogene

Molecular classification: Pseudogene

Overview

Neuroepithelial cell transforming 1 pseudogene (ENSG00000236978, LOC100967223) is classified as a **pseudogene**, a genomic DNA sequence that bears strong similarity to the functional neuroepithelial cell transforming 1 (NET1) gene, but lacks the ability to produce a functional protein[1][3]. Pseudogenes are nonfunctional remnants of genes formed by duplication or retrotransposition events and frequently acquire disabling mutations rendering them incapable of gene expression or protein function[2]. While pseudogenes can sometimes play minor regulatory roles in cell biology—for example, functioning as sources of non-coding RNA or as microRNA decoys—there are no data suggesting such functions for this specific locus[4]. This pseudogene is not a validated drug or therapeutic target, nor a known biomarker for disease surveillance. The entry is considered "incorrect" if used as a therapeutic target, as it does not encode an active protein[2][4].

Other names: LOC100967223ENSG00000236978Neuroepithelial cell transforming 1 (NET1) pseudogene

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