Neurofibromin 1 pseudogene 8 (NF1P8)

Neurofibromin 1 pseudogene 8 (NF1P8) is one of several NF1-related pseudogenes found in the human genome, with others present on chromosomes 2, 14, 15, 18, 21, and 22, in addition to the functional NF1 gene on chromosome 17[4]. Like other pseudogenes, NF1P8 consists of DNA sequences that are homologous to the active NF1 gene but contain mutations, deletions, and insertions that render them non-functional. These pseudogenes do not encode the neurofibromin protein and are not known to have biological or disease-related functions[4]. NF1 pseudogenes have been studied primarily to understand the evolution, gene conversion events, and dispersal mechanisms of the NF1 gene family, but NF1P8 itself is not a receptor, enzyme, transporter, or therapeutic target[4]. Summary: - NF1P8 is a pseudogene, not a protein-coding gene, receptor, or other therapeutic target. - There are no known biological functions, disease roles, drug interactions, mechanisms of action, biomarker roles, or safety concerns associated with this pseudogene. - NF1P8 is not therapeutically targetable and does not play a direct role in human disease or pharmacology[4].

Other names

NF1L2neurofibromin 1-like 2NF1P8