Target intelligence / Profile preview

Neurogenic Differentiation Factor 1 (NEUROD1)

Target: NEUROD1
Molecular classification: Transcription factor, bHLH family member

Overview

Neurogenic differentiation factor 1 (NEUROD1), also known as β2, is a basic helix-loop-helix (bHLH) transcription factor encoded by the NEUROD1 gene in humans. It plays a critical role in neuronal differentiation and maturation, as well as in the regulation of insulin gene expression. NEUROD1 promotes tumor cell proliferation by directly activating metabolic pathways such as the pentose phosphate pathway, and its dysregulation is implicated in several cancers, including colorectal carcinoma.

Other names: β2NDF1

Biological functions

Neuronal differentiationNeuronal maturationInsulin gene regulationCell proliferation

Disease associations

Type II diabetes mellitusCancer

Beyond the preview

Go deeper on Neurogenic Differentiation Factor 1 (NEUROD1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Neurogenic Differentiation Factor 1 (NEUROD1).

Explore the full profile