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Target intelligence / Profile preview
Neuron-specific vesicular protein calcyon (CALY)
- Target
- CALY
- Molecular classification
- Single transmembrane protein
01
Overview
Neuron-specific vesicular protein calcyon is encoded by the CALY gene and plays a role in regulating calcium release after stimulation of purinergic or muscarinic receptors. It interacts with the D1 dopamine receptor indirectly through PSD-95 and is involved in various neuropsychiatric disorders. This molecule is not typically considered a therapeutic target in the same way as receptors or enzymes but is important for understanding dopamine receptor signaling and its implications in neuropsychiatric disorders.
- Other names
- CalcyonCALCYONDRD1IPNSG3D1 dopamine receptor-interacting proteindopamine receptor D1 interacting protein
02
Mechanism of action
Not applicable
03
Biological functions
Signal transductioncalcium release regulationendocytosis regulationclathrin coat assembly
04
Disease associations
Neuropsychiatric disorders (schizophrenia, bipolar disorder, ADHD)
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