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Neuronal cells, or neurons, are the primary functional units of the nervous system responsible for transmitting and processing information. Neuroprotection aims to prevent neuron loss due to injury or disease, while regeneration involves repairing or replacing damaged neurons. Key mechanisms include oxidative stress reduction, excitotoxicity inhibition, mitochondrial protection, and modulation of glial cells. Relevant in various CNS disorders where decreased oxygen/glucose delivery, oxidative stress, mitochondrial dysfunction, excitotoxicity, inflammation, and protein aggregation contribute to neuron loss.
Varies depending on the specific agent. Examples include: Antioxidant defense, anti-excitotoxic action, modulation of glial cells, activation of survival signaling pathways.
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