Neuronal regeneration

Neuronal regeneration" refers to the complex biological process by which neurons regrow or repair themselves after injury or in response to disease. This process involves multiple molecular mechanisms, including gene expression changes, activation of signaling pathways (such as those involving neurotrophic factors like brain-derived neurotrophic factor [BDNF] and its receptor TrkB), epigenetic modifications, and the action of extracellular matrix molecules and growth factors. Transcription factors such as members of the Kruppel-like family (KLFs) also play a regulatory role in axon growth and neuronal survival. While understanding these mechanisms is crucial for developing therapies that promote neuronal repair following damage or degenerative conditions, "neuronal regeneration" itself is not a single molecule or receptor but rather a broad biological phenomenon encompassing many targets and pathways.

Other names

Neuronal regenerationNeural regenerationNerve regeneration