Target intelligence / Profile preview

Neuropeptide S receptor 1 pseudogene

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Overview

The neuropeptide S receptor 1 pseudogene (ENSG00000250756) is a non-functional genomic element and not a protein-coding gene. It does not encode a receptor, is not a therapeutic target, and has no reported biological or disease functions. The therapeutically relevant molecule is neuropeptide S receptor 1 (NPSR1), a G protein-coupled receptor implicated in asthma, inflammation, anxiety, and gastrointestinal function. NPSR1 mediates its effects via binding neuropeptide S, leading to downstream signal transduction through phospholipase C and adenylyl cyclase pathways with roles in intracellular calcium mobilization and cAMP formation. NPSR1 is the target for research, not the pseudogene.

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