Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Neurotensin Receptor 3 (NTS3)
- Target
- NTS3
- Molecular classification
- Type I receptor
01
Overview
Neurotensin receptor 3 (NTS3), also known as sortilin, is a type I receptor that binds neurotensin and other ligands. It plays diverse roles in cellular function, including cell migration, insulin secretion, and cell adhesion. NTS3 is implicated in various physiological processes and pathological conditions such as cancer, diabetes, and neurological disorders. Unlike NTS1 and NTS2, it is not a G protein-coupled receptor and requires propeptide cleavage for activation.
- Other names
- SortilinProsortilin (precursor)Neurotensin receptor 3 propeptide
02
Mechanism of action
N/A
03
Biological functions
Cell migrationInsulin secretionCell adhesionNeuroprotectionRegulation of digestive processesSignal transductionGlucose homeostasis
04
Disease associations
CancerDiabetesNeurological disordersNeuroinflammatory conditionsNeurodegenerative conditions
Beyond the preview
Go deeper on Neurotensin Receptor 3 (NTS3).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Neurotensin Receptor 3 (NTS3).