Target intelligence / Profile preview

Neurotransmitter Release

Molecular classification
Biological Process
01

Overview

Neurotransmitter release is the process by which neurons discharge chemical messengers, known as neurotransmitters, into the synaptic cleft in response to a stimulus. This event is fundamental for synaptic transmission—the communication between neurons or between a neuron and another cell type. It involves a cascade of events starting with an action potential reaching the presynaptic terminal, leading to calcium influx, vesicle mobilization, fusion, exocytosis of neurotransmitters, binding to postsynaptic receptors, and subsequent signal termination.

02

Biological functions

Synaptic transmissionCell signalingNeuromodulation
03

Disease associations

Neurological disordersPsychiatric disordersNeurodegenerative diseases

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