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Neutral alpha-glucosidase AB (GANAB)
- Target
- GANAB
- Molecular classification
- Enzyme, hydrolase
01
Overview
Neutral alpha-glucosidase AB is a catalytic subunit of glucosidase II, involved in the processing of N-glycans by removing alpha-1,3-linked glucose residues. It plays a role in carbohydrate metabolism and protein modification.
- Other names
- Glucosidase II subunit alphaAlpha-glucosidase 2G2ANKIAA0088
02
Mechanism of action
Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins
03
Biological functions
Carbohydrate metabolic processpost-translational protein modificationprotein foldingprotein N-linked glycosylation via asparagine
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