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NFIA antisense RNA 2 (NFIA-AS2)
- Target
- NFIA-AS2
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Other
01
Overview
NFIA antisense RNA 2 (NFIA-AS2) is a long non-coding RNA (lncRNA) transcribed from the antisense strand of the NFIA locus, and annotated as a lncRNA in humans[4]. Antisense RNAs like NFIA-AS2 can overlap or be adjacent to protein-coding genes and are known to modulate gene expression through diverse mechanisms, such as transcriptional interference or RNA-mediated regulation[1][2]. NFIA-AS2 is not known to code for protein and has no established role as a drug target, but has been associated with certain developmental disorders and leukemia[4]. The detailed mechanisms of its function and involvement in disease are still being studied, consistent with the broader roles of non-coding antisense RNAs in regulating gene expression and chromatin state[1][2].
- Other names
- NFIA-AS2NFIA Antisense RNA 2
02
Biological functions
Regulation of gene expressionTranscriptional regulationPotential involvement in developmental processes and cell differentiation
03
Disease associations
Brain malformations with or without urinary tract defectsAcute megakaryocytic leukemia
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