NFKB1 antisense RNA 1 (NFKB1-AS1)

NFKB1-AS1 (ENSG00000260651) is a long non-coding RNA (lncRNA) transcribed antisense to the NFKB1 gene, which encodes the NF-κB p105/p50 transcription factor subunit involved in immune and inflammatory processes. As an antisense RNA, NFKB1-AS1 may have a regulatory function on NFKB1 gene expression, but its specific biological role, clinical significance, or involvement in disease remains largely uncharacterized. This transcript is not currently regarded as a canonical therapeutic target such as a receptor, enzyme, transporter, or ion channel[3]. Essential clarification: "NFKB1 antisense RNA 1" is not the same as "NFKB1," which is a key, druggable transcription factor implicated in immunity and disease[1][5][7]. The antisense transcript has not been established in the literature or databases as a validated target for drug discovery or biological intervention[3].

Other names

NFKB1 antisense RNA 1NFKB1-AS1ENSG00000260651