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Target intelligence / Profile preview
Niban apoptosis regulator 3 (NIBAN3)
- Target
- NIBAN3
- Molecular classification
- Other (protein; not classified as receptor, enzyme, transporter, channel, etc.)
01
Overview
Niban apoptosis regulator 3 (NIBAN3), also known as BCNP1 or FAM129C, is a protein-coding gene found in Homo sapiens, with a prominent expression in immune tissues, especially B cells[3][6][7]. NIBAN3 is a member of the Niban protein family and shares homology with NIBAN1. Experimental functional characterization is limited: some evidence from mouse models and interaction partner analysis suggests a possible role in B-cell development, receptor signaling, and immune regulation, but knockout mouse data do not clearly confirm its biological function[1][4][10]. NIBAN3 is not currently classified as a therapeutic target, and there are no drug development programs or approved therapies directed against it. Its relevance as a disease biomarker, therapeutic safety profile, or drug interactome has not been established to date[3][6][10].
- Other names
- Protein Niban 3BCNP1FAM129CFLJ39802B-cell novel protein 1Niban-like protein 2Protein FAM129Cfamily with sequence similarity 129 member C
02
Biological functions
B-cell signalingcell regulationpossibly apoptosis modulation
03
Disease associations
immune system functionB-cell biologysuggested associations with cancer and immune-related phenotypes
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