Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Nicotinamide Adenine Dinucleotide Pathway (None)
- Target
- None
- Molecular classification
- Metabolic Pathway
01
Overview
The nicotinamide adenine dinucleotide (NAD) pathway refers to the series of biochemical reactions responsible for the synthesis, utilization, and recycling of NAD⁺ and its reduced form NADH. NAD⁺ is a vital coenzyme found in all living cells, playing central roles in metabolism, energy production, DNA repair, gene expression regulation, and cell signaling. Restoring or boosting cellular NAD levels—via supplementation with precursors like NR (nicotinamide riboside), NMN (nicotinamide mononucleotide), niacinamide/nicotinic acid—has been investigated for potential benefits against aging-related conditions and metabolic disorders.
02
Mechanism of action
Boosting NAD+ levels via supplementation with precursors
03
Biological functions
Redox reactionsEnergy productionDNA repairGene expression regulationCell signalingADP-ribosylation reactionsDeacetylationDNA ligase activitySecond messenger synthesis
04
Disease associations
Aging-related diseasesCognitive impairmentCancerMetabolic disordersSarcopeniaFrailtyOxidative cell damage
05
Interacting drugs
Nicotinamide riboside (NR)
3 more in the full profile.
06
Biomarkers
NAD+ levels
Beyond the preview
Go deeper on Nicotinamide Adenine Dinucleotide Pathway (None).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Nicotinamide Adenine Dinucleotide Pathway (None).