Nicotinamide phosphoribosyltransferase pseudogene 1 (NAMPTP1)

Nicotinamide phosphoribosyltransferase pseudogene 1 (NAMPTP1) is a human pseudogene associated with, but distinct from, the functional nicotinamide phosphoribosyltransferase (NAMPT) gene. Unlike the functional NAMPT enzyme, NAMPTP1 does not encode a functional protein, and there is no evidence it acts as a drug target, a therapeutic receptor, enzyme, transporter, or has direct biological functions linked to disease or therapy[1][3][5]. Pseudogenes such as NAMPTP1 can sometimes be expressed, may act as regulatory non-coding RNAs, or serve as molecular decoys for microRNAs, but specific disease roles or applications have not been described for NAMPTP1 to date[5]. All known functional and therapeutic relevance applies to NAMPT (the parental gene) rather than NAMPTP1. Clarifications and rationale: - is_target: false – There is no evidence that NAMPTP1 encodes a therapeutic target or functional protein[1][3]. - is_incorrect: true – If the query intends to cover a druggable or functional target, NAMPTP1 is not appropriate; the correct entity would be the functional enzyme "Nicotinamide phosphoribosyltransferase" (NAMPT), not the pseudogene NAMPTP1[1][3][4]. - molecular_classifications: Labeled as "Other (Pseudogene)" because it does not fit into standard druggable protein families like receptors or enzymes[1][5].

Other names

bA92J19.4NAMPTLPBEF2nicotinamide phosphoribosyltransferase-likepre-B-cell colony enhancing factor 2NAMPTP1