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Target intelligence / Profile preview
Nicotine (N/A)
- Target
- N/A
- Molecular classification
- Alkaloid, Stimulant
01
Overview
Nicotine is a stimulatory alkaloid found in tobacco products. It is highly addictive and toxic in high doses. It acts as an agonist at most nicotinic acetylcholine receptors (nAChRs) and increases neurotransmitter levels in the brain.
02
Mechanism of action
Agonist at most nicotinic acetylcholine receptors (nAChRs)
03
Biological functions
Stimulation of nicotinic acetylcholine receptorsNeurotransmitter modulation
04
Disease associations
AddictionCardiovascular diseaseLung disease
05
Safety considerations
AddictionCardiovascular effectsPotential for poisoning in high doses
06
Interacting drugs
Nicotine replacement therapy (NRT)
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