NIFK pseudogene 6 (NIFKP6)

NIFK pseudogene 6 (NIFKP6) is classified as a pseudogene in the human genome[3][5]. It is related by sequence to the protein-coding gene NIFK (nucleolar protein interacting with the FHA domain of MKI67), which encodes a protein known to interact with the Ki-67 antigen involved in cell cycle regulation[2][7]. Unlike its protein-coding counterpart, NIFKP6 does not encode a functional protein. Pseudogenes such as NIFKP6 are generally considered genomic DNA segments that share high sequence similarity with functional genes but contain mutations or defects that preclude their translation into a functional product[5]. Some pseudogenes have been found to exert biological effects through regulatory RNA mechanisms, but there is currently no published evidence indicating any functional, regulatory, or pathogenic role for NIFKP6 specifically[3][5]. It is not considered a therapeutic target, receptor, enzyme, or biomarker, and it has no known disease associations.

Other names

MKI67IPP6MKI67 (FHA domain) interacting nucleolar phosphoprotein pseudogene 6nucleolar protein interacting with the FHA domain of MKI67 pseudogene 6NIFKP6