Target intelligence / Profile preview

NIFK pseudogene 7 (NIFKP7)

Target
NIFKP7
Molecular classification
Pseudogene
01

Overview

**NIFK pseudogene 7 (NIFKP7)** is a human pseudogene located on chromosome 2[1][2]. It is related by sequence and homology to the functional NIFK gene, which encodes a nucleolar protein that interacts with the FHA (forkhead-associated) domain of the human Ki-67 antigen (MKI67), a well-known marker of cell proliferation[1][3][4]. Unlike the protein-coding NIFK gene, NIFKP7 is classified as a pseudogene and is not known to encode a functional protein[1][2]. Pseudogenes such as NIFKP7 generally do not have therapeutic relevance, biological function, or disease association, and are not considered drug targets[1][2]. **Note:** - Information is very limited for NIFK pseudogene 7 as it is non-coding and not implicated in known disease or therapeutic settings. All reported aliases refer to variants on the pseudogene naming. - The functional gene, NIFK, should not be confused with NIFKP7. NIFK plays a role in cell cycle regulation and binds to Ki-67, but this is unrelated to the pseudogene described here[3][4][7][8].

Other names
MKI67IPP7MKI67 (FHA domain) interacting nucleolar phosphoprotein pseudogene 7Nucleolar protein interacting with the FHA domain of MKI67 pseudogene 7NIFKP7
02

Mechanism of action

Not applicable (pseudogene, not a drug target)

03

Biological functions

None (pseudogene; no known protein-coding function)
04

Disease associations

None established
05

Safety considerations

None
06

Interacting drugs

None known
07

Biomarkers

None established

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