NIMA-related kinase 4 pseudogene 1 (NEK4P1)

NIMA-related kinase 4 pseudogene 1 (NEK4P1) is a pseudogene, meaning it is a DNA sequence similar to the protein-coding gene NEK4 but is considered non-functional and does not produce an active protein. No evidence supports NEK4P1 as a therapeutic target, biomarker, or functionally relevant molecule in human biology or disease. The active gene in this family is NEK4, a serine/threonine kinase involved in cell cycle regulation and mitochondrial morphology[4][5]. NEK4P1, however, should not be confused with NEK4 and is not associated with the known biological functions or disease links of the NEK4 protein.\n\nThere may be confusion because pseudogenes are sometimes included in bioinformatics resources, but they do not have established roles in disease, drug response, or cellular signaling. No information supports their utility in pharmacology, therapeutics, or diagnostics.\n\nIf your interest is in an active kinase or a therapeutic target, you likely meant NEK4, not NEK4P1. NEK4P1 is *not a drug target, enzyme, receptor, transporter,* or otherwise functional molecule. NEK4P1 is not a valid therapeutic or biological target; this is a pseudogene and should not be used for target selection in drug discovery or molecular biology. If you seek relevant biology or pharmacology, refer to the active gene NEK4[4][5].

Other names

NEK4P1NIMA (never in mitosis gene a)-related kinase 4 pseudogene 1