Nitric oxide synthase 2 pseudogene 2 (NOS2P2)

Nitric oxide synthase 2 pseudogene 2 (NOS2P2) is a pseudogene related to the gene encoding inducible nitric oxide synthase (NOS2, iNOS). Pseudogenes typically arise due to duplication or mutation of functional genes and are generally not translated into functional proteins. While some pseudogenes have emerging roles in regulating gene expression via antisense RNA or truncated dominant-negative proteins, NOS2P2 is not known to encode a functional protein, nor is it considered a therapeutic target or disease biomarker. NOS2P2 may be referenced in genetics research due to its relationship to NOS2. The canonical functional target in clinical and drug development contexts is nitric oxide synthase, inducible (NOS2/iNOS).

Other names

NOS2B

None for NOS2P2, as it is a pseudogene and not a drug target. Mechanisms for NOS2 inhibitors (e.g., reduced NO production) do not apply.