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NKAP domain containing 1 (NKAPD1)
- Target
- NKAPD1
- Molecular classification
- Other (uncharacterized protein), Possesses an NKAP domain and lysine-rich region, Not classified as receptor, enzyme, transporter, ion channel, or typical transcription factor
01
Overview
NKAP domain containing 1 (NKAPD1) is a human protein encoded by the NKAPD1 gene located on chromosome 11q23.1. It contains the NKAP domain (NF-kappa-B-activating protein) and a lysine-rich region immediately afterward. NKAPD1 is expressed ubiquitously at moderate levels, with higher expression in the brain and thyroid. It has several transcript variants that encode different isoforms. The functional role of NKAPD1 remains largely uncharacterized; although structurally related to NKAP and inferred to participate in nuclear functions and protein-protein interactions, no direct biological activities or disease links are established for NKAPD1 specifically.
- Other names
- NKAPD1C11orf57chromosome 11 open reading frame 57NKAP domain containing protein 1FLJ10726uncharacterized protein NKAPD1
02
Mechanism of action
Not applicable; no drugs targeting this protein are known.
03
Biological functions
Unknown for NKAPD1 itselfinferred to be possibly involved in nuclear functions, protein-protein interactions, RNA processing or binding due to presence of the NKAP domain, but definitive biological functions remain uncharacterized
04
Disease associations
Unknown for NKAPD1No direct disease associationpublished work on related proteins suggests possible links to immune development and cancer, but these are unproven for NKAPD1 itself
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