NMNAT1 pseudogene 3 (NMNAT1P3)

NMNAT1 pseudogene 3 (NMNAT1P3) is a genomic sequence sharing high similarity with the NMNAT1 gene, but it is typically nonfunctional and does not encode a functional protein. NMNAT1P3 is one of several NMNAT1-related pseudogenes listed on multiple chromosomes; these were likely formed as a result of gene duplication or retrotransposition events[3]. While the functional NMNAT1 gene encodes a nuclear enzyme essential for NAD biosynthesis and is critical for cellular energy metabolism and DNA repair, pseudogene copies such as NMNAT1P3 do not produce active enzymes and have no established role in metabolism or disease. There is currently no evidence that NMNAT1P3 acts as a therapeutic target or has biological activity[3][1]. If you are seeking information on the functional protein (Nicotinamide mononucleotide adenylyltransferase 1, NMNAT1), please clarify, as its properties, molecular classification, and therapeutic relevance differ substantially[1][3][4].

Other names

NMNAT1P3NMNAT1 pseudogene 3