NOL4L divergent transcript (NOL4L-DT)

NOL4L divergent transcript (NOL4L-DT) is a long non-coding RNA (lncRNA) gene located near the nucleolar protein 4-like (NOL4L) locus. The “divergent transcript” designation refers to its transcriptional orientation, which is opposite to a nearby protein-coding gene from a shared promoter region—a feature common in mammalian genomes where transcription occurs in both directions from a promoter[7]. While the protein-coding gene NOL4L has been implicated in some fusion events in acute leukemia, the function, expression profile, and clinical relevance of NOL4L-DT remain unknown. Available evidence from databases and gene annotations indicates that NOL4L-DT does not encode a protein and currently has no established biological or therapeutic role[5][1][3][7]. - No PDB structure exists for NOL4L-DT. - No documented Gene Ontology (GO) functional annotations beyond general RNA/protein binding for this lncRNA[1][5]. - Most information comes from genome-wide annotation databases rather than experimental studies. If you require information on the protein-coding NOL4L gene (nucleolar protein 4-like), more is known regarding its location, expression pattern, and rare involvement in gene fusions in leukemia[3]; however, the “NOL4L divergent transcript” specifically refers to a noncoding RNA gene without well-characterized function or disease association[5].

Other names

NOL4L-DTNOL4L divergent transcript

Not applicable, as there are no known drugs targeting this transcript