Target intelligence / Profile preview

Non-bulbar Dermal Sheath Fibroblast (NBDS cells)

Target: NBDS cells
Molecular classification: Mesenchymal cell, Fibroblast

Overview

Non-bulbar dermal sheath fibroblasts (NBDS cells) are a specialized subpopulation of fibroblast-like cells derived from the dermal sheath of hair follicles, specifically the region above the bulb and below the sebaceous gland canal. They are mesenchymal in origin and characterized by their morphology, location, and collagen production capabilities. NBDS cells are involved in ECM support and wound healing, and they are being explored for therapeutic applications in skin and tendon regeneration.

Other names: Non-bulbar DS fibroblastsNBDS fibroblasts

Biological functions

Collagen synthesisExtracellular matrix supportWound healingTissue repair

Disease associations

Wound healingSkin regenerationTendon regeneration

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