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Non-histone chromosomal protein HMG-14 pseudogene (ENSG00000224555) is a processed pseudogene in the human genome, derived from the parent gene encoding HMGN1 (high mobility group nucleosomal binding domain 1/HMG-14). Pseudogenes are DNA sequences similar to known genes but are typically non-functional due to mutations or truncations. While initially thought to be "genomic fossils," some pseudogenes can be transcribed and may affect gene expression by regulatory RNA mechanisms, though this is not established for ENSG00000224555 specifically[2][3]. This locus does not code for a protein and is not involved in canonical receptor, enzyme, or transporter functions. It is not currently associated with human disease nor used as a therapeutic target.
None (not applicable; pseudogenes are not pharmacological targets)
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