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Target intelligence / Profile preview
Non-tuberculous Mycobacteria (NTM)
- Target
- NTM
- Molecular classification
- Bacteria
01
Overview
Non-tuberculous mycobacteria (NTM) are a diverse group of bacteria within the genus *Mycobacterium* that do not cause tuberculosis (*Mycobacterium tuberculosis*) or leprosy (*Mycobacterium leprae*). NTM are ubiquitous in the environment and can cause a range of infections, particularly in individuals with pre-existing lung conditions or weakened immune systems. Treatment is challenging due to antibiotic resistance and requires prolonged multi-drug regimens.
- Other names
- Environmental MycobacteriaAtypical MycobacteriaMycobacteria Other Than Tuberculosis (MOTT)
02
Mechanism of action
Antibiotic mechanisms vary depending on the drug; target bacterial cell wall synthesis, protein synthesis, or DNA replication.
03
Biological functions
Environmental survivalInfection
04
Disease associations
Pulmonary diseaseLymphadenitisSkin and soft tissue infectionsDisseminated disease
05
Safety considerations
Antibiotic resistanceProlonged treatment durationDrug-related side effectsTreatment failure
06
Interacting drugs
Azithromycin
3 more in the full profile.
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