Target intelligence / Profile preview

Norovirus GII.4 Virus-Like Particle (None)

Target: None
Molecular classification: Viral capsid protein, Virus-like particle, Recombinant protein

Overview

Norovirus GII.4 virus-like particles (VLPs) are non-infectious, recombinant protein assemblies that mimic the structure of native noroviruses. These VLPs are composed solely of the major capsid protein VP1, which self-assembles into icosahedral particles resembling the authentic virus. VLPs elicit strong immune responses and are promising candidates for vaccine development.

Other names: Norovirus GII.4 VLPGII.4 VLPNorovirus VP1 capsid protein

Mechanism of action

N/A

Biological functions

Capsid formationAntigen presentationHBGA binding

Disease associations

Acute gastroenteritisNorovirus infection

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