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Not applicable—this is not a molecular target (MPI (Myocardial Perfusion Imaging))

Target
MPI (Myocardial Perfusion Imaging)
01

Overview

The term "Myocardial perfusion" refers to the blood flow to the heart muscle, which is measured and evaluated through myocardial perfusion imaging (MPI), a diagnostic nuclear medicine procedure. This is fundamentally different from a molecular target suitable for drug development. Myocardial perfusion imaging is a diagnostic test, not a therapeutic target. The procedure uses radioactive tracers (such as 201Tl-chloride, 99mTc-sestamibi, and 99mTc-tetrofosmin) to visualize blood flow to the heart muscle and detect areas of reduced perfusion. The imaging technique helps clinicians diagnose conditions like coronary artery disease and assess myocardial viability, but perfusion itself is a physiological parameter being measured rather than a molecular entity that can be pharmacologically targeted.

02

Biological functions

Blood supply to the heart muscle
03

Disease associations

Indicator for coronary artery disease diagnosisAssessment of myocardial viability

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