Novel antisense transcript to ERN1

ENSG00000286629 encodes a long non-coding RNA that is transcribed in the antisense orientation relative to the ERN1 gene. As with other natural antisense transcripts, its primary known role is the regulation of gene expression, typically through interactions with chromatin, transcript stability, and possibly epigenetic modification. Antisense RNAs can influence their corresponding sense gene (here, ERN1) by modifying transcription rates, altering transcript processing, changing RNA stability, or affecting chromatin structure, often via changes in histone modification or DNA methylation. No direct evidence supports its function as a therapeutic target, disease biomarker, or drug target, and there are no known drugs interacting with this transcript. Sequence and function information are very limited; it is not a canonical therapeutic target, receptor, enzyme, or protein-coding gene.

Other names

ENSG00000286629Antisense to ERN1