Novel HLA class I pseudogene fragment (ENSG00000229836)

ENSG00000229836, known as the “novel HLA class I pseudogene fragment,” is a human pseudogene fragment located in the major histocompatibility complex (MHC) Class I region. Pseudogenes in this region are non-functional remnants of previously active HLA class I-related genes, arising through gene duplications and subsequent mutations. This particular fragment shares sequence homology with the HLA class I family, which encompasses highly polymorphic molecules essential for antigen presentation in the immune system, but it lacks protein-coding potential or known physiological function. It does not encode a protein, is not considered a therapeutic target, and has no direct disease associations, biomarker value, or safety concerns. This pseudogene and others in the HLA class I region are studied primarily for evolutionary insight into the structure and diversification of the HLA gene family and do not participate in immune signaling or disease pathways.

Other names

GC06M031275

None (not a protein-coding or functional regulatory gene)