Novel keratin associated protein 21 family pseudogene

The "novel keratin associated protein 21 family pseudogene" (ENSG00000238257) is classified as a human pseudogene related to the KRTAP21 family. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they arise from previously functional genes due to mutations such as frameshifts or premature stop codons. The functional KRTAP21 genes are involved in the structure of hair shafts, specifically the cross-linking of keratin intermediate filaments through disulfide bonding, creating mechanical strength in hair. However, this pseudogene does not code for a functional protein and has no known role in disease, biological processes, or drug interaction. If a user is seeking information on an actionable or druggable target, reference should instead be made to active protein-coding family members such as Keratin associated protein 21-1 (KRTAP21-1).

Other names

KRTAP21Pnovel KRTAP21 pseudogeneKRTAP21 family pseudogene