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Novel myxovirus resistance protein pseudogene (ENSG00000250505)

Target
ENSG00000250505
Molecular classification
Other (Pseudogene), related to the dynamin-like GTPase (Mx protein) family
01

Overview

This entry represents a pseudogene homologous to the myxovirus resistance protein 1 (MX1/MxA), which belongs to the dynamin-like GTPase family and is well known for its antiviral roles in mammals[1][2][4]. However, pseudogenes like ENSG00000250505 do not code for functional proteins, and there is no evidence that this genomic locus serves any biological function, acts as a therapeutic target, or interacts with drugs. The confusion arises from its similarity to functional genes that encode active antiviral proteins (such as MX1/MxA), which are critical for innate immune response against a range of viruses including influenza and other RNA viruses[1][2][4]. Unless later found to have regulatory RNA or other rare functions, the designation as a "novel myxovirus resistance protein pseudogene" means it should not be used as a canonical target in drug discovery or clinical diagnostics.

Other names
Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) pseudogeneLOC100422637ENSG00000250505

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