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Novel transcript, antisense to aldehyde dehydrogenase 2 (ENSG00000298157)
- Target
- ENSG00000298157
- Molecular classification
- Long non-coding RNA (lncRNA), other (antisense RNA)
01
Overview
ENSG00000298157 designates a long non-coding RNA (classified as a novel transcript) mapped antisense to the protein-coding ALDH2 gene locus. It is annotated based on its genomic position but lacks experimental characterization regarding its function, involvement in disease, or utility as a drug target. There is currently no evidence for direct biological or therapeutic relevance of this transcript, and no known aliases beyond its descriptive name. ALDH2, the host gene, is well characterized, but ENSG00000298157 itself is only genomically annotated[4]. In summary, ENSG00000298157 is not a conventional therapeutic target and should not be confused with ALDH2, a protein-coding gene and enzyme with established roles in disease and therapy[1][2][4].
- Other names
- Novel transcript, antisense to ALDH2antisense lncRNA at ALDH2 locus
02
Mechanism of action
None reported. No mechanism of action for drugs described for this RNA.
03
Biological functions
Unknown. lncRNAs commonly have regulatory or epigenetic roles, but no validated function is described for this specific transcript.
04
Disease associations
Unknown. No validated disease association reported for this specific lncRNA. Note: ALDH2, the sense protein-coding gene, is involved in cancer, alcohol metabolism, and drug response[1][2][5].
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