Novel transcript, antisense to ARHGAP39 (ENSG00000255456)

Novel transcript, antisense to ARHGAP39" (ENSG00000255456) is a long non-coding RNA identified as transcribed from the antisense strand at the ARHGAP39 locus[4]. No evidence suggests that this antisense transcript encodes a protein or functions as a therapeutic target (e.g., receptor, enzyme, transporter). Its potential biological role may involve regulation of ARHGAP39 expression via mechanisms such as chromatin modification or transcriptional interference, general to antisense RNAs[2]. ARHGAP39 itself (sense gene) is a Rho GTPase-activating protein involved in cell migration, apoptosis, and neural development, and is an emerging target in cancer therapy[1][3][5]; however, the antisense transcript’s function, clinical relevance, or druggability have not been established in the literature.

Other names

ENSG00000255456novel transcript, antisense to ARHGAP39