Novel transcript, antisense to cadherin-12 (ENSG00000286961)

Novel transcript, antisense to cadherin-12" (ENSG00000286961) is a long non-coding RNA (lncRNA) identified as being transcribed from the DNA strand opposite to the **CDH12** (cadherin-12) gene[1]. Antisense lncRNAs are known to influence expression and regulation of their corresponding sense genes through several mechanisms, including chromatin modification, transcriptional interference, and RNA-mediated regulation[2][3]. While the precise functional role of this particular transcript is not characterized in current databases, studies on antisense transcripts in general indicate they can modulate the rates of production, processing, and stability of their sense transcripts by altering chromatin state, such as increasing histone acetylation and buffering the activity of chromatin-modifying complexes[2][3]. There is no evidence that this particular antisense transcript encodes a protein, acts as a therapeutic target, or is involved directly in human disease; rather, it is categorized as a regulatory non-coding RNA, whose biological effects (if characterized) would likely include epigenetic and transcriptional regulation at the CDH12 locus[1][2][3].

Other names

Novel transcript, antisense to CDH12ENSG00000286961CDH12-AS