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Novel transcript, antisense to CCDC12 (ENSG00000294040)

Target
ENSG00000294040
Molecular classification
Long noncoding RNA (lncRNA), natural antisense transcript
01

Overview

This gene encodes a long noncoding RNA (lncRNA) that is transcribed antisense to the protein-coding CCDC12 (Coiled-coil domain containing 12) gene. Antisense lncRNAs are RNA molecules transcribed from the opposite DNA strand relative to a gene, commonly overlapping with their sense partner at least partially. Many antisense transcripts participate in regulation of gene expression at the transcriptional, post-transcriptional, and epigenetic levels, although biological functions of most individual lncRNAs remain uncharacterized. Known mechanisms for natural antisense transcripts include transcriptional interference, RNA masking, double-stranded RNA-dependent silencing, and chromatin remodeling. No specific function, biomarker role, or therapeutic relevance has been documented for ENSG00000294040 as of now.

Other names
antisense to CCDC12lncRNA antisense to CCDC12
02

Biological functions

Regulation of gene expression (putative, based on general function of antisense lncRNAs)possible roles may include transcriptional interference, RNA masking, RNA interference, and chromatin remodeling
03

Disease associations

Other

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