novel transcript, antisense to CFAP61

ENSG00000300020 refers to a transcript annotated as being antisense to the protein-coding gene CFAP61. Unlike CFAP61, which encodes a component of the calmodulin- and spoke-associated complex crucial for sperm flagellum structure and function[1][2], this antisense transcript does not code for a known protein and has no established biological or therapeutic relevance. It is not recognized as a therapeutic target, nor is there evidence linking it to drug interactions, disease mechanisms, or biomarker utility. Its functional significance remains uncharacterized, and no literature supports a direct role in human disease or physiology. The entry likely reflects an uncharacterized or predicted non-coding transcript in the genomic vicinity of CFAP61, rather than a distinct, validated target suitable for therapeutic intervention[3].