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The gene \"novel transcript, antisense to CHURC1\" (ENSG00000303859, LOC105370534) is annotated as a long non-coding RNA gene predicted to occur antisense to the protein-coding gene CHURC1 on chromosome 14. Available public resources only indicate that this is a lncRNA locus and the nearest protein-coding gene is SPTB, located over 10kb away. There is no functional, disease, or pharmacological information, and the transcript is not recognized as a protein, receptor, enzyme, or transporter. No evidence supports this as a validated therapeutic target, and its biological significance remains undetermined in peer-reviewed resources[5][7]. This locus is not the well-annotated CHURC1 gene (sometimes called Churchill domain containing 1), which is a protein-coding gene involved in neural development and cell movement regulation[3]. ENSG00000303859 is instead a non-coding transcript with no established molecular or pathological function.
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