novel transcript, antisense to Epithelial stromal interaction 1

The entity labelled "novel transcript, antisense to EPSTI1" (ENSG00000298154) is an uncharacterized long non-coding RNA transcribed from the DNA strand opposite to the Epithelial stromal interaction 1 (EPSTI1) gene locus. There is currently no evidence that this transcript produces a functional protein, has a known cellular or biological role, or is recognized as a therapeutic or diagnostic target in human disease. Research and functional annotation overwhelmingly focus on EPSTI1 itself (a protein-coding gene involved in immune regulation and cancer biology), rather than any antisense transcript at this locus. The term "antisense to EPSTI1" refers to transcription from the DNA strand opposite to that encoding the EPSTI1 gene. Many such antisense transcripts are non-coding and remain unstudied unless specifically shown to play a biological role (e.g., in gene regulation). EPSTI1 (not the antisense transcript) is a protein-coding gene with important roles in immunity, inflammation, and cancer. Databases (Ensembl, GeneCards) and literature do not list ENSG00000298154 as a recognized protein, drug target, or biomarker. According to standard nomenclature and curation guidelines, “novel transcript, antisense to EPSTI1” should not be considered a canonical target entry until further functional evidence is established.

Other names

ENSG00000298154Antisense lncRNA to EPSTI1

None known