novel transcript, antisense to glutamate receptor, metabotropic 1 (ENSG00000299793)

This entry corresponds to a "novel transcript, antisense to GRM1" (ENSG00000299793), a non-coding RNA species transcribed from the opposite DNA strand of the GRM1 locus. Such antisense RNAs can sometimes modulate the expression of the sense (protein-coding) gene through mechanisms like RNA interference, transcriptional interference, or chromatin modification, but no evidence exists that this particular transcript plays a major functional role or is clinically relevant. It is important not to confuse this RNA with the GRM1 protein itself, which encodes a G protein-coupled receptor implicated in neurotransmission and some cancers.

Other names

GRM1-AS