Novel transcript, antisense to intercellular adhesion molecule 5 (ENSG00000294616)

This entry refers to a long non-coding antisense RNA transcript located at the ICAM5 gene locus. ICAM5, also known as intercellular adhesion molecule 5 (telencephalin), is a membrane glycoprotein conferring neuronal adhesion functions and is expressed predominantly in the telencephalon of the brain. The biological relevance, expression profile, or function of the antisense transcript to ICAM5 (ENSG00000294616) has not been clearly established in the literature or functional databases. Generally, antisense RNAs may play a regulatory role in gene expression, but specific roles for this transcript are currently uncharacterized. The protein-coding ICAM5 gene is well studied and is involved in neuronal adhesion, synaptic development, and cognitive-related processes. The transcript referenced here is non-coding and antisense, and as such does not encode a protein or function as a canonical drug target. Entries like "novel transcript, antisense to ICAM5" should be used with caution in target selection or curation pipelines, as they may be artifacts or uncharacterized RNA species. This "novel transcript, antisense to ICAM5" is a non-coding RNA transcript with no established function, drug interaction, or biomarker role. It is not considered a therapeutic target, and the entry likely reflects a computational annotation rather than a validated molecule of direct biomedical relevance.