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Novel transcript, antisense to SHC2

Molecular classification
Long noncoding RNA (lncRNA), Natural antisense transcript
01

Overview

ENSG00000297401 is a long noncoding RNA (lncRNA) transcribed antisense to the SHC2 gene. As with many natural antisense transcripts, it may be involved in regulation of the sense SHC2 transcript, potentially via chromatin remodeling, transcriptional interference, or regulation of transcript stability. However, this particular lncRNA has not been characterized as a protein, enzyme, receptor, or therapeutic target. There is currently no evidence supporting its utility in disease diagnostics, therapeutics, or drug targeting. Natural antisense lncRNAs are a widespread genomic feature, and generally function by diverse epigenetic regulatory mechanisms, but very few have been validated as therapeutic targets or biomarkers.

Other names
ENSG00000297401lncRNA antisense to SHC2Novel transcript, antisense to SHC2
02

Biological functions

Regulation of sense gene expressionpossible epigenetic modulationchromatin remodeling

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