Novel transcript, antisense to trefoil factor 1 (ENSG00000306128)

This molecule is a long non-coding RNA transcribed antisense to the TFF1 gene locus. It shows alternative splicing and contains large segments of the antisense strand from TFF1 introns 1 and 2. No protein product has been identified. Antisense transcription of non-coding RNAs such as this one can regulate the expression of the corresponding sense gene, sometimes through gene silencing or transcriptional interference. No direct evidence links this transcript to therapeutic targeting or disease, and its biological role remains unclear except for a possible regulatory effect in specific tissues. Most of the core information is sourced from databases and primary molecular profiling; there is no evidence this molecule is a canonical, actionable therapeutic target. It is correctly classified as a novel antisense lncRNA rather than a protein-coding gene or classical drug target.

Other names

Novel transcript antisense to TFF1antisense TFF1 lncRNA