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Novel transcript, antisense to WWOX" (ENSG00000287106) is a **long non-coding RNA** (lncRNA) gene transcribed in the antisense orientation relative to the WWOX gene. LncRNAs of this kind are part of a widespread phenomenon in vertebrate genomes where natural antisense transcripts (NATs) are expressed from the strand opposite a protein-coding gene. These antisense RNAs can regulate their sense counterparts via mechanisms such as transcriptional interference, RNA masking, and modulation of splicing or stability, thus influencing gene expression[1][3]. There are no established functions, disease associations, or therapeutic targeting mechanisms specific to this transcript, nor is it currently recognized as a target for any drugs[7]. This transcript primarily serves as a genomic annotation of non-coding RNA with potential regulatory roles but insufficient evidence for direct therapeutic significance or clinical application.
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