Novel transcript, antisense to ZNF253

This molecule is a long non-coding RNA transcribed in the antisense orientation to the ZNF253 gene. Long non-coding antisense transcripts frequently function via a range of gene regulatory mechanisms, including interfering with transcription, modulating mRNA stability, altering chromatin states, and affecting the expression of their sense counterparts[2][4][5]. While many antisense lncRNAs have emerging relevance in disease regulation and cell biology, there is no specific characterized function, disease linkage, or therapeutic relevance currently reported for "novel transcript, antisense to ZNF253" (ENSG00000267565)[3].

Other names

Novel transcript antisense to ZNF253Antisense to ZNF253

Transcriptional interference, RNA masking, Chromatin remodeling, dsRNA-dependent silencing (such as RNA interference). These are general mechanisms by which antisense transcripts regulate their corresponding sense genes, not necessarily specific to this transcript[2][4][5].